Inspirex® Liver
Bioengineered human liver graft for life-saving transplantation
PRESSING NEED
More liver grafts for transplant
The wait for a liver transplant is a battle against time. Many patients spend years on the transplant waiting list, only to face rejection, complications, or even death while waiting for an organ to become available. Inspirex® Liver offers a lifeline to those who have exhausted all other options.
MEDICAL BREAKTHROUGH
Inspirex® Liver
Generated using our groundbreaking xenogeneic cross-circulation platform, Inspirex® Liver is a bioengineered human liver graft with whole organ functionality and anatomical compatibility for clinical transplantation.
IMPACT
Transforming the future of liver transplant
Liver transplants have only increased incrementally over the past 20 years. Inspirex® Liver holds potential to dramatically increase the number of liver transplants and eliminate liver transplant waitlist mortality in the U.S.
- Organ Procurement & Transplant Network/Scientific Registry of Transplant Recipients. Annual Data Report, 2024.
REFERENCES
- Wu WK, Tumen A, Stokes JW, Ukita R, Hozain A, Pinezich M, O’Neill JD, et al. Cross-circulation for extracorporeal liver support in a swine model. ASAIO. 2022; 68(4): 561-570.
- Wu WK, Ukita R, Patel YJ, Cortelli M, Trinh VQ, Ziogas IA, et al. Xenogeneic cross-circulation for physiological support and recovery of ex vivo human livers. Hepatology. 2023; 78(3): 820-834.
- Shishido Y, Tracy KM, Wu WK, Cortelli M, Petrovic M, Harris TR, et al. Characterization of porcine immunoglobulin deposition in human livers recovered using xenogeneic cross-circulation. ASAIO. 2024.