ExMatrico® Peptides (Matrikynes®) | Extracellular Matrix Peptides for Tissue Repair

ExMatrico® Peptides (Matrikynes®) are bioactive extracellular matrix peptides that support regenerative signaling pathways involved in tissue repair, cellular renewal, and recovery.


Tissue regeneration requires extracellular matrix signaling

Throughout the body, extracellular matrices (ECMs) store bioactive signals called matrikines that drive tissue repair by triggering intracellular pathways that mediate cell differentiation and proliferation.

Delivery of matrikines significantly improves tissue repair and healing by stimulating the body’s innate reparative physiology.

These tissue regeneration peptides help support the body’s innate reparative responses across multiple tissue environments.


Matrikynes® activate regenerative pathways

Matrikynes® are proprietary combinations of matrikine peptides that activate pro-regenerative mechanisms to modulate inflammation, reverse tissue damage, and accelerate cellular renewal.

Leveraging systemic physiology, these peptides tissue repair technologies support regenerative processes involved in healing and functional tissue recovery.


Topical applications

Independent clinical studies validate Matrikynes® efficacy in topical applications, including statistically significant improvements in barrier function, barrier repair, skin density, hydration, hyperpigmentation, lines and wrinkles.

Matrikynes® significantly increases skin density and dermal thickness, restoring lost collagen – the building block to healthier, youthful skin – in just 4 weeks.


  • SOURCE: Clinical evaluation of Matrikynes®: A novel cosmetic ingredient comprised of matrikine peptides

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