
ExMatrico® Peptides (Matrikynes®) | Extracellular Matrix Peptides for Tissue Repair
ExMatrico® Peptides (Matrikynes®) are bioactive extracellular matrix peptides that support regenerative signaling pathways involved in tissue repair, cellular renewal, and recovery.

Tissue regeneration requires extracellular matrix signaling
Throughout the body, extracellular matrices (ECMs) store bioactive signals called matrikines that drive tissue repair by triggering intracellular pathways that mediate cell differentiation and proliferation.
Delivery of matrikines significantly improves tissue repair and healing by stimulating the body’s innate reparative physiology.
These tissue regeneration peptides help support the body’s innate reparative responses across multiple tissue environments.
Matrikynes® activate regenerative pathways
Matrikynes® are proprietary combinations of matrikine peptides that activate pro-regenerative mechanisms to modulate inflammation, reverse tissue damage, and accelerate cellular renewal.
Leveraging systemic physiology, these peptides tissue repair technologies support regenerative processes involved in healing and functional tissue recovery.

Topical applications
Independent clinical studies validate Matrikynes® efficacy in topical applications, including statistically significant improvements in barrier function, barrier repair, skin density, hydration, hyperpigmentation, lines and wrinkles.
Matrikynes® significantly increases skin density and dermal thickness, restoring lost collagen – the building block to healthier, youthful skin – in just 4 weeks.


- SOURCE: Clinical evaluation of Matrikynes®: A novel cosmetic ingredient comprised of matrikine peptides
AwardS & Recognition
Industry honors for game-changing tissue regeneration
Award
Best Breakthrough Technology Ingredient
Recognizes the creation of a new ingredient/technology or innovative use of an existing ingredient/technology associated with the formulation of cosmetic products.
Recognition
Leading Regenerative Skin Care
Xylyx Bio and Sweet Chemistry are transforming skin care with regenerative medicine. Led by Dr. John O’Neill, they use matrikines and upcycled bovine peptides to repair skin, reduce inflammation, and reverse aging. Sweet Chemistry’s Elasticity Reinforcing Cream shows impressive results in improving skin density.