Inspirex™
Bioengineered Organ Grafts
Bioengineered human whole organ grafts for clinical transplantation
Inspirex™ is a next-generation platform advancing bioengineered organ grafts for life-saving transplantation and expanded access to transplantable organs.
About Inspirex™
Organ Grafts
Bioengineered human whole organ grafts for life-saving transplantation
FIRST-IN-CLASS BIOLOGICS
Bioengineered to save lives
The XC™ Platform transforms discarded and otherwise unutilized donor organs to generate functional, anatomically compatible organ grafts for transplantation.
Through regenerative medicine and whole organ bioengineering, Inspirex™ advances new possibilities in organ replacement and transplant care.
Inspirex™ Lung
Inspirex™ Liver
Inspirex™ Kidney
Inspirex™ Heart
APPROACH
Groundbreaking biotechnology
Leveraging xenogeneic cross-circulation with a porcine bioreactor, our XC™ Platform provides the integrated normothermic systemic physiologic regulation needed to bioengineer Inspirex™ organ grafts for transplantation.
Energy substrates
Nutrients provided by glucoregulation and carbohydrate metabolism of porcine bioreactor
Circulating factors
Systemic supply of cytokines, growth factors, hormones, exosomes, and other extracellular signals
Biochemical regulation
Homeostatic balance of physiologic variables, including acid-base, ions, fluid balance, and neuroendocrine axes
Metabolic clearance
Elimination of lactate, urea, and other metabolites and toxins by porcine bioreactor
Energy substrates
Nutrients provided by glucoregulation and carbohydrate metabolism of porcine bioreactor
Circulating factors
Systemic supply of cytokines, growth factors, hormones, exosomes, and other extracellular signals
Biochemical regulation
Homeostatic balance of physiologic variables, including acid-base, ions, fluid balance, and neuroendocrine axes
Metabolic clearance
Elimination of lactate, urea, and other metabolites and toxins by porcine bioreactor
Value propositions
Significant benefits for key stakeholders
Patients
Lives saved & extended life expectancy
Providers
Informed decision-making & increased operational efficiency
Hospitals
Improved clinical care & outcomes
