Inspirex®
Organ Grafts
Bioengineered human whole organ grafts for clinical transplantation
About Inspirex®
Organ Grafts
Bioengineered human whole organ grafts for life-saving transplantation
FIRST-IN-CLASS BIOLOGICS
Bioengineered to save lives
Our XC™ Platform transforms discarded otherwise unutilized donor organs into fully functional, anatomically compatible bioengineered whole organ grafts for life-saving transplantation.
Inspirex® Lung
Inspirex® Liver
Inspirex® Kidney
Inspirex® Heart
APPROACH
Groundbreaking biotechnology
Leveraging xenogeneic cross-circulation with a porcine bioreactor, our XC™ Platform provides the integrated normothermic systemic physiologic regulation needed to bioengineer Inspirex® organ grafts for transplantation.
Energy substrates
Nutrients provided by glucoregulation and carbohydrate metabolism of porcine bioreactor
Circulating factors
Systemic supply of cytokines, growth factors, hormones, exosomes, and other extracellular signals
Biochemical regulation
Homeostatic balance of physiologic variables, including acid-base, ions, fluid balance, and neuroendocrine axes
Metabolic clearance
Elimination of lactate, urea, and other metabolites and toxins by porcine bioreactor
Energy substrates
Nutrients provided by glucoregulation and carbohydrate metabolism of porcine bioreactor
Circulating factors
Systemic supply of cytokines, growth factors, hormones, exosomes, and other extracellular signals
Biochemical regulation
Homeostatic balance of physiologic variables, including acid-base, ions, fluid balance, and neuroendocrine axes
Metabolic clearance
Elimination of lactate, urea, and other metabolites and toxins by porcine bioreactor
Value propositions
Significant benefits for key stakeholders
Patients
Lives saved & extended life expectancy
Providers
Informed decision-making & increased operational efficiency
Hospitals
Improved clinical care & outcomes
