Harnessing systemic physiology to save lives

Tissue regeneration involves complex systemic interactions between cells, extracellular matrices, and soluble mediators, including potent bioactive signals called matrikines. Our Matrikynes® are proprietary combinations of matrikine peptides that promote functional tissue repair by activating intracellular signaling pathways that facilitate cell differentiation, matrix synthesis, and restoration of tissue homeostasis.

A major obstacle to discovering and developing effective drugs is the lack of physiologically relevant, predictive cell-based models. Our In Matrico® models and assays integrate primary human cells and primary tissue-specific extracellular matrices into standardized, reproducible physiological systems that recapitulate the biochemical and mechanical environments of human tissues for predictive 3D drug testing, yielding actionable test results consistent with those in patients.