The cell environment company

Environment matters.

Just as the environment matters at the macro scale for plants and animals, it is essential at the micro scale for cells. Recognizing the importance of the native cellular microenvironment, Xylyx Bio is harnessing the power of tissue-specific extracellular matrix, the body’s native cell environment, for both drug discovery and tissue regeneration.

Cell Culture

Xylyx Bio's suite of native tissue-specific extracellular matrix (ECM) products bring the most physiologic cell environments possible to the petri dish to radically improve early-stage drug discovery efforts.

Tissue Regeneration

With potential to address multiple unmet clinical needs, Xylyx Bio is utilizing its proprietary matrix bioactives to pursue R&D on clinically-oriented products derived from tissue-specific ECM.

News

Xylyx Bio Announces Global Expansion

Xylyx Bio announced partnerships with 9 international distributors to meet growing demand. Additional distributors provide scientists working in drug screening, cancer research, 3D cell models and toxicology with the ability to improve the human relevance of in vitro cell models.

East River BioSolutions Announces Rebrand to Xylyx Bio

East River BioSolutions, a biotech company specializing in cell-specific extracellular matrix biomaterials, today announced its rebrand to Xylyx Bio. The new branding underscores the Company’s focus on accelerating science for improved human health.

East River BioSolutions releases NativeCoat™ ECM substrates

East River BioSolutions announced the release of NativeCoat™ ECM – a novel line of 2D in vitro cell culture coatings comprised of native tissue-derived extracellular matrix (ECM) that enables scientists to study cells in their tissue-specific microenvironments, leading to more physiologically relevant testing and thus more accurate and actionable scientific results.

East River BioSolutions Awarded NIH SBIR Phase I Grant

East River BioSolutions is proud to announce that it has been awarded SBIR Phase I grant from the NIIH. The award will support further development of a fibrotic lung-specific cell culture substrate that will allow scientists to build more physiologically relevant in vitro models of IPF.

Xylyx Bio Announces Global Expansion

East River BioSolutions Announces Rebrand to Xylyx Bio

What they’re saying

“ We were looking for a product to use for engineering cartilage tissue. We used the TissueSpec® Cartilage ECM Hydrogel to encapsulate chondrocytes within the 3D tissue environment the cells are exposed to in native cartilage. Chondrocytes grew really well, and these tissue constructs have developed mechanical and biochemical properties and histological staining similar to native articular cartilage.”

Bob Nims, PhD, Columbia University

“ As a cancer cell biologist it is always challenging to develop ideal cancer cell culture condition in 3D model to study cell-signaling pathways. Xylyx Bio offers bone and liver derived hydrogels, the two major sites for the prostate cancer metastasis. Those TissueSpec® ECM Hydrogels are a perfect solution to study the effect of metastatic microenvironment on prostate cancer cell signaling. ”

Goutam Chakraborty, Ph.D, MSKCC

“ Though our relationship is new, working with Xylyx Bio has been a pleasure. They are incredibly responsive and helpful with both scientific and non-scientific inquiries and are willing to go above and beyond to work with customers! ”

Amanda Khoo, PhD, Brown University