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3D cell and organoid culture

Maintenance of stem cells and organoids in culture requires the appropriate tissue-specific ECM niche. TissueSpec® ECM Hydrogels, including heart, liver, lung, and more, provide high-fidelity niches that support stem cell-matrix interactions and regulate cell maintenance, proliferation, and differentiation.

Bone ECM cell culture substrate

MTSBN101 TissueSpec® Bone ECM Hydrogel

Heart ECM cell culture substrate

MTSHT101 TissueSpec® Heart ECM Hydrogel

Intestine ECM cell culture substrate

MTSIN101 TissueSpec® Intestine ECM Hydrogel

Kidney ECM cell culture substrate

MTSKY101 TissueSpec® Kidney ECM Hydrogel

Liver ECM cell culture substrate

MTSLV101 TissueSpec® Liver ECM Hydrogel

Lung ECM cell culture substrate

MTSLG101 TissueSpec® Lung ECM Hydrogel

Skin ECM cell culture substrate

MTSSK101 TissueSpec® Skin ECM Hydrogel

Related Resources

3D lung tumor model with lung extracellular matrix to predict drug efficacy
Application note: IN SITE™ Metastasis Kit to accelerate anticancer drug development
Poster: TissueSpec® ECM Hydrogels for predictive 3D models of human cancer
Poster: TissueSpec® Extracellular Matrix Substrates for 3D Cell Culture
TissueSpec® Lung ECM Hydrogel Product Datasheet
TissueSpec® Liver ECM Hydrogel Product Datasheet
TissueSpec® Intestine ECM Hydrogel Data
The regulation of growth and metabolism of kidney stem cells with regional specificity using extracellular matrix derived from kidney. Biomaterials. (2013)
Hybrid Gel Composed of Native Heart Matrix and Collagen Induces Cardiac Differentiation of Human Embryonic Stem Cells without Supplemental Growth Factors. J Cardiovasc Transl Res. (2011)
Engineering bone tissue from human embryonic stem cells. Proc Natl Acad Sci U S A. (2012)
Efficient generation of lung and airway epithelial cells from human pluripotent stem cells. Nat Biotechnol. (2014)